In 1986, to awaken America to the AIDS crisis and to honor the friends he lost, Brent Nicholson Earle runs the perimeter of the United States. In The American Run for the End of AIDS, Brent runs almost a marathon a day for 20 months straight. After enduring blisters, exhaustion, ignorance, and fear, he returns home to his own HIV diagnosis. Though the run finishes, Brent’s activism never stops.