In the city of South Los Angeles a Ghostbuster franchise gets decommissioned and no longer can be at their station. They find a way to keep their jobs but now they must rebuild their names from scratch and put their division back on the map!

After the closure of their local division, a diverse group of ghostbusters on the south side of Los Angeles are forced to adapt when they are unexpectedly faced with a demonic entity, summoned by a neighborhood street gang.